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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRP1B All Species: 8.79
Human Site: S325 Identified Species: 19.33
UniProt: Q14684 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14684 NP_055871.1 758 84411 S325 H F N R K R L S K L I K K F Q
Chimpanzee Pan troglodytes XP_001144331 758 84400 S325 H F N R K R L S K L I K K F Q
Rhesus Macaque Macaca mulatta XP_001104749 757 84489 S325 P F N R K R L S K L I K K F Q
Dog Lupus familis XP_535600 705 78213 F298 L S K L I K K F Q D L S E A G
Cat Felis silvestris
Mouse Mus musculus Q91YK2 724 80564 R314 K S T P P F N R K R L C R L V
Rat Rattus norvegicus XP_228076 733 81457 C318 P F N R K R L C R L V R K F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511992 745 81602 C316 P F N R R R L C K L I R K F Q
Chicken Gallus gallus NP_001026505 755 84389 F326 L Y K L V K K F Q D L A E G I
Frog Xenopus laevis NP_001079701 613 69077 G210 F L Q A V T S G V F Q T I L E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJZ7 687 78978 D284 I D D I E K L D S G F D E E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798604 679 76515 V276 F Q S L A K G V Y P M P D L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 87.7 66.3 N.A. 61.6 64.1 N.A. 53.1 47 39.7 N.A. N.A. 24.4 N.A. N.A. 26.6
Protein Similarity: 100 99.7 90.2 75 N.A. 74 76.1 N.A. 68 65.1 55.1 N.A. N.A. 40.2 N.A. N.A. 43.4
P-Site Identity: 100 100 93.3 0 N.A. 6.6 66.6 N.A. 73.3 0 0 N.A. N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 26.6 N.A. 20 86.6 N.A. 86.6 33.3 6.6 N.A. N.A. 33.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 19 0 0 0 10 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 10 0 19 0 10 10 0 10 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 28 10 10 % E
% Phe: 19 46 0 0 0 10 0 19 0 10 10 0 0 46 0 % F
% Gly: 0 0 0 0 0 0 10 10 0 10 0 0 0 10 10 % G
% His: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 10 0 0 0 0 0 37 0 10 0 10 % I
% Lys: 10 0 19 0 37 37 19 0 46 0 0 28 46 0 0 % K
% Leu: 19 10 0 28 0 0 55 0 0 46 28 0 0 28 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 46 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 28 0 0 10 10 0 0 0 0 10 0 10 0 0 0 % P
% Gln: 0 10 10 0 0 0 0 0 19 0 10 0 0 0 46 % Q
% Arg: 0 0 0 46 10 46 0 10 10 10 0 19 10 0 0 % R
% Ser: 0 19 10 0 0 0 10 28 10 0 0 10 0 0 0 % S
% Thr: 0 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 19 0 0 10 10 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _